Protein Details: Glycine receptor subunit alpha-2

Protein ID

ICDB_Pro_0421

Protein Name

Glycine receptor subunit alpha-2

Gene Name

GLRA2

Organism

Homo sapiens (Human)

Length

452 amino acids

AlphaFoldDB

AF-P23416-F1-model_v4.pdb

Function

Sequence

MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK

PDB Structures

5BKF 5BKG 7KUY 7L31

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

226;228;236-241;249;295

Disease

Intellectual Developmental Disorder;X-Linked;Syndromic;Pilorge Type and Autism Spectrum Disorder